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Home | Wellcome Leap: Unconventional Projects. Funded at Scale.

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NEW $50M PROGRAM LEARN MORE NEW $2M PRIZE Wellcome Leap Announces $2M Prize in $50M Quantum for Bio Challenge Program LEARN MORE A breakthrough engine for health. At global scale. Wellcome Leap builds bold, unconventional programs, and funds them at scale. Programs optimized to deliver breakthroughs in human health over 5 – 10 years and demonstrate seemingly impossible results on seemingly impossible timelines.Wellcome Leap is a global ARPA for health. In 6 years, executing 15 programs in 30 countries. $55M Program What if millions of women with heart disease were no longer left without answers? LEARN MORE $50M Program What if ensuring resilience in the maternal and infant gut microbiome can help support healthy neurodevelopment? LEARN MORE $50M Program the missed vital sign What if we could reduce the time it takes to get effective treatment for heavy menstrual bleeding from 5 years to 5 months? LEARN MORE $50M Program care What if endocrinology could prevent Alzheimer's? LEARN MORE $50M Program Untangling Addiction What if we treated addiction like we treat cancer, as a curable, biological illness? LEARN MORE $60M Program Dynamic Resilience What if our health span matched our life span? LEARN MORE $50M Supported Challenge Q4Bio What if we could develop new algorithms that deliver quantum advantage for health? LEARN MORE $50M Program SAVE What if we could shorten and improve training and not all surgical providers needed to be MDs? LEARN MORE $50M Program In Utero What if we could reduce the number of stillborn babies by half by detecting emerging complications in utero? LEARN MORE R3 Global What if a distributed network of biofoundries could produce mRNA biologics for cancer, Zika, or RA, and also surge capacity in the advent of a pandemic? LEARN MORE $50M Program Multi-Channel Psych What if we could double the number of people who receive an effective treatment for depression? On the first try. LEARN MORE $55M Program Delta Tissue What if we could predict future disease progression for an individual so as to target treatments today? LEARN MORE $45M Program 1kD What if we've been approaching the first 3 years of a child's development all wrong? LEARN MORE $50M Program HOPE What if we could bioengineer a kidney that restores enough function to eliminate dialysis? LEARN MORE Researchers working together to solve problems they can’t solve alone. A new worldwide network of scientists and engineers is demonstrating how philanthropy can leverage a 60-year proven innovation model to solve urgent global problems. Now over 170 organizations on 6 continents, representing more than 1,500,000 researchers. The world’s largest research network, ready for instant activation. Network shown at midpoint of first five programs. READ MORE https://test-wellcome-leap.pantheonsite.io/wp-content/uploads/2024/12/leap_sizzle_final-1080p.mp4https://test-wellcome-leap.pantheonsite.io/wp-content/uploads/2025/02/sizzle_16-9_edit-720p.mp4 Using a 60+ year proven model of innovation. Wellcome Leap is built on a unique model of innovation practiced at DARPA.For more than six decades, this model has been an uninterrupted engine of breakthrough innovation. It is not a discovery science model, but neither is it a pure application model.It sits firmly at the intersection of the two. Read how we’re Changing the Business of Breakthroughs. Learn more about Wellcome Leap's model of innovation. Read how we’re Changing the Business of Breakthroughs. Learn more about Wellcome Leap's model of innovation. Next Steps Be Part of the Future of Health Join Our Mission Become part of the team driving global health innovation. Explore Our ProgramsDive into our groundbreaking health initiatives. Stay InformedSign up for updates and breakthroughs in health innovation. This kind of work is hard.The hard is what makes it great. Sign up for updates Menu Programs Focused Antibiotics VISIBLE FORM The Missed Vital Sign CARE Untangling Addiction Dynamic Resilience Q4Bio SAVE In Utero R3 Global MCPsych Delta Tissue 1kD HOPE Women’s Health Team News Stories This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. We use a third party provider, Mailchimp, to deliver our newsletters. For information about how we handle your data, please read our Privacy Notice. You can unsubscribe at any time using the link in the emails you receive.Connect with us. Twitter X linkedinCreated with Sketch.

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Wellcome Leap: Unconventional Projects. Funded at Scale.

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NEW $50M PROGRAM LEARN MORE NEW $2M PRIZE Wellcome Leap Announces $2M Prize in $50M Quantum for Bio Challenge Program LEARN MORE A breakthrough engine for health. At global scale. Wellcome Leap builds bold, unconventional programs, and funds them at scale. Programs optimized to deliver breakthroughs in human health over 5 – 10 years and demonstrate seemingly impossible results on seemingly impossible timelines.Wellcome Leap is a global ARPA for health. In 6 years, executing 15 programs in 30 countries. $55M Program What if millions of women with heart disease were no longer left without answers? LEARN MORE $50M Program What if ensuring resilience in the maternal and infant gut microbiome can help support healthy neurodevelopment? LEARN MORE $50M Program the missed vital sign What if we could reduce the time it takes to get effective treatment for heavy menstrual bleeding from 5 years to 5 months? LEARN MORE $50M Program care What if endocrinology could prevent Alzheimer's? LEARN MORE $50M Program Untangling Addiction What if we treated addiction like we treat cancer, as a curable, biological illness? LEARN MORE $60M Program Dynamic Resilience What if our health span matched our life span? LEARN MORE $50M Supported Challenge Q4Bio What if we could develop new algorithms that deliver quantum advantage for health? LEARN MORE $50M Program SAVE What if we could shorten and improve training and not all surgical providers needed to be MDs? LEARN MORE $50M Program In Utero What if we could reduce the number of stillborn babies by half by detecting emerging complications in utero? LEARN MORE R3 Global What if a distributed network of biofoundries could produce mRNA biologics for cancer, Zika, or RA, and also surge capacity in the advent of a pandemic? LEARN MORE $50M Program Multi-Channel Psych What if we could double the number of people who receive an effective treatment for depression? On the first try. LEARN MORE $55M Program Delta Tissue What if we could predict future disease progression for an individual so as to target treatments today? LEARN MORE $45M Program 1kD What if we've been approaching the first 3 years of a child's development all wrong? LEARN MORE $50M Program HOPE What if we could bioengineer a kidney that restores enough function to eliminate dialysis? LEARN MORE Researchers working together to solve problems they can’t solve alone. A new worldwide network of scientists and engineers is demonstrating how philanthropy can leverage a 60-year proven innovation model to solve urgent global problems. Now over 170 organizations on 6 continents, representing more than 1,500,000 researchers. The world’s largest research network, ready for instant activation. Network shown at midpoint of first five programs. READ MORE https://test-wellcome-leap.pantheonsite.io/wp-content/uploads/2024/12/leap_sizzle_final-1080p.mp4https://test-wellcome-leap.pantheonsite.io/wp-content/uploads/2025/02/sizzle_16-9_edit-720p.mp4 Using a 60+ year proven model of innovation. Wellcome Leap is built on a unique model of innovation practiced at DARPA.For more than six decades, this model has been an uninterrupted engine of breakthrough innovation. It is not a discovery science model, but neither is it a pure application model.It sits firmly at the intersection of the two. Read how we’re Changing the Business of Breakthroughs. Learn more about Wellcome Leap's model of innovation. Read how we’re Changing the Business of Breakthroughs. Learn more about Wellcome Leap's model of innovation. Next Steps Be Part of the Future of Health Join Our Mission Become part of the team driving global health innovation. Explore Our ProgramsDive into our groundbreaking health initiatives. Stay InformedSign up for updates and breakthroughs in health innovation. This kind of work is hard.The hard is what makes it great. Sign up for updates Menu Programs Focused Antibiotics VISIBLE FORM The Missed Vital Sign CARE Untangling Addiction Dynamic Resilience Q4Bio SAVE In Utero R3 Global MCPsych Delta Tissue 1kD HOPE Women’s Health Team News Stories This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. We use a third party provider, Mailchimp, to deliver our newsletters. For information about how we handle your data, please read our Privacy Notice. You can unsubscribe at any time using the link in the emails you receive.Connect with us. Twitter X linkedinCreated with Sketch.